Molgramostim is a recombinant human granulocyte macrophage colony stimulating factor (rHGM-CSF), produced by recombinant DNA technology from E.coli. It is 127 amino acid protein, non-glycosylated, and has a molecular weight ofapproximately 14.5kD.
Indications
1. In patients receiving myelosuppressive therapy ( cancer chemotherapy ) to reduce the severity of neutropenia, thereby reducing the risk of infection and allowing better adherence to the chemotherapeutic regimen;
2. In patients undergoing autologous or syngeneic bone marrow transplantation to accelerate myeloid recovery (Molgramostim does not improve overall survival or increase time to relapse);
Pharmaceutical particulars
Sterile and white lyophilized powder to be reconstituted with a diluent (Sterile Water for Injection) for injection, presented in vials.