|Place of Origin:||China|
PGE1 for injection,
A wide variety of pharmacological effects of Alprostadil are vasodilation, inhibition of platelet aggregation, and stimulation of intestinal and uterine smooth muscle. Alprostadil induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries.
In vitro, Alprostadil has been shown to cause dose-dependent smooth muscle relaxation in isolated corpus cavernosum and corpus spongiosum preparations.
In human studies using Doppler duplex ultrasonography, administration of Alprostadil resulted in an increase in peak systolic flow velocities.
1. Cardiovascular disorders:
Maintaining the patency of the ductus arteriosus in neonates with congenital heart disease until surgery is possible2.
2. Peripheral vascular disease:
Alprostadil can be administered by intra-arterial or intravenous infusion3.
3. Erectile Dysfunction:
Intracavernous injection4, intra-urethral application5and non-invasive delivery systems including topical and needle-less applications6.
Befarâ, Caverjectâ, Edexâ, Lipleâ, Minprogâ, MUSEâ, Palusâ, Prostandinâ, Prostavasinâ, ProstinâVR, ProstineâVR, Prostivasâ, Sutineâ, Topiglan®.
Alprostadil can be supplied as:
Specs are available upon request